We are committed to the welfare and health of people and, above all, to the eradication of diseases in less developed societies
We are committed to the welfare and health of people and, above all, to the eradication of diseases in less developed societies
BIOMATERIALS
Our group develops biocompatible glass materials with osteo-inducing characteristics. These materials are being tested in bone repair as well as coatings of titanium implants
We also develop hybrid organic-inorganic materials (Ormosils) with biocompatible properties and to be capable of forming hydroxyapatite on their surface. These studies help us to know the interactions of biomolecules with inorganic materials based on the silica-phosphorus-calcium system
HEALTH
We investigated new materials of micro and nanoparticles with controlled and functionalized porosities for use in mucoadhesive films transporting drugs capable of preventing the infection and development of AIDS
NEWS
Smart Films for pH-responsive drugs release used in vaginal applications for AIDS prevention read more
PUBLICATIONS
Free amino groups of the silane are required to achieve a smart pH-responsive material. This is only achieved in those materials containing a silane chemisorbed monolayes
CONFERENCES
Amine free groups of silane monolayers show a smart response pH-dependent for drug delivery
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Chitosan compacts with Tenofovir may be an appropriate formulation for preventing the sexual transmission of HIV due to its good mucoadhesión, sustained drug release and moderate swelling with erosion that ensures patient comfort
VIEW MOREPROJECTS
This project will develop intelligent PH-controlled release films for the prevention of sexually transmitted AIDS. The films will be formed by a biocompatible organic matrix and micro-nanoparticles of silicon oxycarbides with micro-meso porosoties and with mono-bi-trimodal pore size distributions. These particles will be coated with polymers sensitive to the pH of the medium and in whose pores are the selective drugs of preventing AIDS.
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The objetive is to combine a highly porous metal scaffold, made by EMB sintering technology, and tissue engineering elements (biomaterials, signalling molecules and stem cells) to produce a bioactive implant for maxillofacial surgery, and to test this implant in a concrete clinical setting: reconstruction of full-thick mandibular defects.
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